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This is not surprising given that the diets effect on the lipid profiles of patients without FH is still controversial

However, it is contraindicated in patients with chronic liver failure due to concerns about hepatic encephalopathy and associated symptoms like malaise, nausea, appetite loss, and abdominal cramps (23)

Research suggests that the pathogenesis of IBD is multifactorial, involving genetic predisposition, gut microbiota dysbiosis, environmental factors, and immune system abnormalities (26, 27)

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In cases where dyslipidaemia is resistant to treatment or statin intolerance/contraindications exist, intestinal cholesterol absorption inhibitors such as ezetimibe, or, in high CV risk patients, PCSK9 inhibitors (Alirocumab or Evolocumab), may be considered

Individuals who suffer from trimethylaminuria (fish odor syndrome) , as supplementation can worsen symptoms