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"L-carnitine in hemodialysis: systematic review." J Am Soc Nephrol 2002;13:708-14

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Riboflavin also plays a role in thyroxine metabolism, and its deficiency may contribute to mental illness, because riboflavin activates vitamin B6, leading to lower thyroxine levels, reduced hypothalamic serotonin synthesis, and decreased levels of S-adenosylmethionine (SAMe), because of disrupting the folate-methylation pathways involved in SAMe synthesis, all of which are associated with antidepressant effects, consequently, low levels of these compounds may cause depression ( Figure 4 ) (, )

A larger longitudinal study could further clarify the role of NE in tremor modulation

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However, fortified plant-derived foods are available (i.e., certain types of bread and cereals, some vegetables), as well as milk infant formulas [31]