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In particular, while REV-ERBs act as transcriptional repressors of BMAL1 expression, RORs positively regulate the expression of BMAL1 by binding to sites Retinoic acid receptor-related Orphan Receptor Element (RORE) elements in the BMAL1 gene promoter
Treating Parkinsons Disease via Activation of BDNF/TrkB Signaling Pathways and Inhibition of Delta-Secretase
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