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To determine whether mere exposure to IL-1 is sufficient to generate a pro-arrhythmogenic substrate, ventricular myocytes were incubated for 24 h with IL-1 and the number of spontaneous contractile events (NSE), an index of cellular arrhythmic activity, was measured after pacing the cells during 10 min at either 0.5 or 3 Hz

Eur J Nutr 42:2942 Nenadis N, Boyle S, Bakalbassis EG, Tsimidou M (2003) An experimental approach to structure-activity relationships of caffeic and dihydrocaffeic acids and related monophenols

Stressful life events and psychosomatic symptoms in fibromyalgia syndrome and rheumatoid arthritis

4-7,42 An elevated serum alanine aminotransferase (ALT) level is seen in up to 14% of adults

Abbreviations aCSF artificial cerebral spinal fluid AldoA fructose-bisphosphate aldolase A ANLS astrocyte-to-neuron lactate shuttle APC/C anaphase-promoting complex/cyclosome ATP adenosine triphosphate BNIP3 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3L BNIP3-like CAMK2a calcium/calmodulin-dependent protein kinase II alpha CBF cortical blood flow COX2 cyclooxygenase-2 COX4 cytochrome c oxidase subunit 4 DCA dichloroacetate DEC1 deleted in esophageal cancer 1 DIV days in vitro ECAR extracellular acidification rate ETC electron transport chain F2,6P2 fructose 2,6-bisphosphate FIH factor inhibiting HIF G6P glucose-6-phosphate G6PD glucose-6-phosphate dehydrogenase GBE1 1,4-alpha-glucan branching enzyme 1 GC gas chromatography GLUT1 glucose transporter 1 GSH glutathione GYS1 glycogen synthase 1 HK2 hexokinase 2 HIF hypoxia-inducible factor HRE hypoxia response element IL1 interleukin-1 beta I/R ischemia/reperfusion LC liquid chromatography LDH lactate dehydrogenase LonP1 lon protease 1 MCA middle cerebral artery MCP-1 monocyte chemoattractant protein-1 MCT monocarboxylate transporter MS mass spectrometry MSEA metabolite set enrichment analysis NAD nicotinamide adenine dinucleotide NADP nicotinamide adenine dinucleotide phosphate NRF2 NF-E2-related factor 2 O 2 oxygen OCR oxygen consumption rate OGD oxygen-glucose deprivation OHSC organotypic hippocampal slice culture OXPHOS oxidative phosphorylation PDHA1 pyruvate dehydrogenase E1 alpha subunit PDK1 pyruvate dehydrogenase kinase 1 PFK1 phosphofructokinase 1 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 PGC-1 peroxisome proliferator-activated receptor gamma coactivator 1 alpha PGK1 phosphoglycerate kinase 1 PGM1 phosphoglucomutase 1 PHD prolyl-4-hydroxylase domain PHI PHD inhibitor PPP pentose-phosphate pathway PYGB glycogen phosphorylase B ROS reactive oxygen species TCA tricarboxylic acid TNF tumor necrosis factor alpha VEGF vascular endothelial growth factor References 1.Kierans SJ, Taylor CT

These factors can foster ED cures in cases of cavernous nerve injury
