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According to the Global Burden of Disease (GBD) Study 2019, the number of individuals living with PD more than doubled from 2.5 million in 1990 to over 6.1 million in 2016, with projections exceeding 12 million by 2040 (Zhong and Zhu, 2022)
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Small RNAs (siRNA and miRNA) are key regulators of gene expression, involved in most developmental and stress response processes in eukaryotic cells (Leisegang et al., 2017)
When FLAG-tagged wild-type (WT) and aa72-86 SLC25A39 plasmids were transfected into AFG3L2 knockout A549 cells, only WT SLC25A39 expression was significantly elevated by AFG3L2 loss, while aa72-86 expression remained unaffected (Fig
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