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10.3389/fnagi.2024.1347987 Front

3.5.4 Modulation of the tumor microenvironment ITCs also exert anticancer effects by altering the tumor microenvironment

The most used inducers of ferroptosis, erastin, and RSL3, are inhibitors of system X C and direct inhibitors of GPX4, respectively (Stockwell et al., 2017)

The digestive system can take up MGO from exogenous sources, which include dietary MGO, and MGO formed by the gut microbiome

DOPA decarboxylase converts DOPA to dopamine, dopamine -hydroxylase converts dopamine to norepinephrine, and phenylethanolamine N -methyltransferase converts norepinephrine to epinephrine

Hartung I
