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During inflammation, the endothelial barrier is compromised due to the opening of intercellular gaps, leading to an increased vascular permeability which allows leukocytes and plasma proteins to enter tissues [64]
[DOI] [PubMed] [Google Scholar] 105.Peier a, Kosinski j, Cox-york k, et al

Given that EV recovery rates are low, their use in drug delivery may be even more expensive than Provenge

From all above, research into the metabolic reprogramming of TC is quite worthy for its clinical value

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Ther Clin Risk Manag 7:1-11, 2010
