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If there are complicating medical or untreated comorbidities some patients will be in therapy longer.
To date, five types of PMs have been identified (polymyxins A, B, C, D, and E), but only two, PMB and CST (polymyxin E), have been used in clinical practice [13, 14]
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Mice were euthanized on the last day of 2 week observation, and blood was collected for complete blood count (TEK-II MINI Auto Hematology Analyzers, TECOM Science Corporation, China) and serum biochemistry (Hitachi 7600 Automatic Biochemistry Analyzer, Hitachi Ltd., Japan) analyses
TB-500 has a half-life of approximately 710 days, meaning plasma levels remain detectable for 34 weeks after a single injection
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