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doi: 10.1002/(SICI)1098-1136(199606)17:2 3.0.CO;2-7

Importantly, peptide analogs with stapling moieties present at the hydrophobic interface (1914, 1919, 1921, 2015, 2017) had limited improvement or even loss of activity compared to LD2, suggesting that substitution of these interfacial residues disrupted key hydrophobic interactions (Table 1)

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These peptides can be synthesized in labs to serve as treatments to improve fat loss

Its selective action on adipose tissue lets researchers study fat loss independently of effects on muscle, bone, or glucose metabolism

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