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2020;48:D103141

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Deviations 1 log 2 titer were considered to be within natural technical variation of the BMD assay

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However, interestingly, deletion of the glucocorticoid receptor specifically in Osterix-expressing bone marrow osteoprogenitor cells increases BMAT and reduces cortical and trabecular bone mass under ad libitum feeding, calorie restriction conditions, and with aging (390, 391), suggesting that excessive or deficient glucocorticoid signaling in the BMAd progenitors can lead to similar outcomes