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Description
Chem 55 1990 Synthesis of Chiral Piperazin-2-ones as Model Peptidomimetics DiMaio J and Belleau B J

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Variation in the mid region was increased in the 50M48 hour treatment relative to the 10M72 hour treatment

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it is carried out in a buffered solution to ensure a stable pH, since the reaction proceeds more rapidly under slightly basic conditions

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