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702 These results suggest that liproxstatin-1 improves recovery from SCI by inhibiting endothelial cell ferroptosis and maintaining the integrity of the blood-spinal barrier

Anti-inflammatory therapy offers novel intervention strategies for EDC

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It also promotes angiogenesis via IL-6 and IL-8 and fosters an immunosuppressive TME by upregulating tryptophan-2,3-dioxygenase (TDO2), which enhances kynurenine production

Especially for animals with an overburdened liver, animals that take medication for a long time or recover from anesthesia, and older animals, because the own production of glutathione decreases while the need increases

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Donnelly C.G., Finno C.J