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These sORF produce bioactive peptides, collectively known as mitochondrial-derived peptides (MDP), which have a wide range of physiological functions and can explain how mitochondria communicate within and between cells in a specific disease environment (5)

For the analysis of lamellipodia, cells were transfected with pCAH-Lifeact-EGFP 65 using Lipofectamine 3000 (Invitrogen), cultured for 1 day and then cultured in glass-bottom dishes (IWAKI) for 1 day

10.1074/jbc.m110.164160 J

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TLRs, another major class of PRRs highly expressed on macrophages, neutrophils, and DCs, also contribute to antifungal immunity by recognizing distinct C

To further observe the transformation of peptides in living cells, we conjugated a fluorescent indicator Rhodamine B (RhoB) to peptides and synthesized RS and RC as analogs of NSBSO and NCBSO respectively (Additional file 1: Figs