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[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Jonas E.A

The identification of oxygen as the ultimate electron acceptor after the formation of disulphide bonds in proteins means that the products of the reduction of oxygen have to be removed to prevent damage to cellular components

It has indeed been demonstrated that p300/CBP transcriptional co-activator proteins (two central players in coordinating and integrating multiple signal dependent events with the transcription apparatus [215, 216]) bind to NRF2 in response to OS induced by arsenite and acetylate several Lys residues within the Neh1, the DNA binding region of NRF2, stabilizing it, increasing protein abundance, and promoting NRF2 nuclear localization [146, 214, 217] (Fig

Tomu00e1s M, Rolo J, Gaspar C, Palmeira-de-Oliveira A, Simu00f5es S, Katz DF, et al

GDF15 and FGF21 were measured in the mouse serum by ELISA kits (Abcam, ab216947

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