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Given the limitations of existing treatments, there is a need for innovative and more effective interventions to repair cartilage and delay the progression of OA, while minimizing the adverse effects

Outside joint tissue, inflammation follows a different pattern that shapes how it is studied

10.1126/science.1219855 Science 282 YuR.LiuT.JinS

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Biomarkers are biological changes that can be measured to indicate the presence or absence of a disease or the risk of developing symptoms from a disease

IGF-1 overexpressed mesenchymal stem cells can promote the migration, growth, and proliferation of bone marrow-derived mesenchymal stem cells by activating the AKT/SFRP2 signaling pathway, and inhibit cell apoptosis (125)