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5 In serious cases, glutamate-induced excitotoxicity can cause neuronal death throughout the central nervous system

As the metabolic pathways related to homocysteine became delineated other important polymorphic variants were described, such as the thermolabile variant of the folate metabolizing enzyme, methylenetetrahydrofolate reductase (MTHFR) (5, 6)

Safety and potential side effects As with any biologically active substance, a responsible approach to its use is crucial

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There are 2 ways to start treatment with ARISTADA: Option 1: You will receive 1 dose of ARISTADA INITIO in combination with a single dose of oral aripiprazole

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