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Ergothioneine, a naturally occurring sulfur-containing amino acid, serves as the hub, connecting the other antioxidants in the formula, and has an extremely unique ability to function on-demand, concentrating in damaged tissues

doi: 10.2165/00003495-199448020-00002 Pubmed Abstract CrossRef Google Scholar View reference in article 68 HoxhaBHoxhaMDomiEGervasoniJPersichilliSMalajVet al

298 In contrast, HSPA1A was consistently upregulated upon mild heat shock in these cell lines, suggesting a more predictable induction of the HSR

Emodin promotes autophagy and prevents apoptosis in Sepsis-associated encephalopathy through activating BDNF/TrkB signaling

doi: 10.3390/biology11081127 51 KimH.KimS

Despite being a cosmopolitan species and its origin being tropical Asia (69), it is present but not abundant in the tropics
