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N-Isobutyrylcysteine, a thiol designed to deliver more free thiol than NAC does, was tested against placebo in 637 individuals with COPD for 6 months, and found to have no effect on respiratory exacerbations

[DOI] [PMC free article] [PubMed] [Google Scholar] Ogboo B

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The experiment was conducted in flasks containing 100 mg/L of pesticides and cultivated for 12 days at 30 C

Disruption of iron homeostasis plays a significant role in COPD pathogenesis, exacerbating both lipid peroxidation and oxidative stress (146)

[212] identified three potent GSTO1 inhibitors containing chloroacetamide, namely C1-27, C1-31, and C4-10 (Figure 12DF), via extensive small molecule screening, biochemical analysis, and X-ray crystallography