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Intravenous injections should be given slowly and stopped on the first signs of adverse reaction

The fecal microbiota of patients with primary biliary cholangitis (PBC) causes PBC-like liver lesions in mice and exacerbates liver damage in a mouse model of PBC

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Most standard wellness IVs fall within a narrower window, while advanced therapies such as NAD+ IV therapy sit at the higher end of the spectrum

However, further studies are necessary before the regulation of barrier permeability can be introduced into clinical practice 104

The effect remains gradual and cumulative rather than instant