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The optimal protocol is to inject first thing in the morning, after an overnight fast of at least 8 hours

There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

Also, dont inject expired B12

This is why some of those who have had weight loss surgery or surgery to remove part of the stomach have difficulty absorbing the vitamin B12 they need from foods

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