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doi: 10.1016/0005-2728(85)90160-4

Hydro Ceramide: Supports skin renewal, reinforces the natural barrier, and soothes irritation

Reynertson KA, Garay M, Nebus J, Chon S, Kaur S, Mahmood K, Kizoulis M, Southall MD

This enhances Ca 2+ influx, which subsequently activates ADP-ribosyltransferase (ARTD1/PARP1), leading to energy-consuming poly-ADP-ribosylation and caspase cleavage, not to induce apoptosis, but paradoxically to inhibit it
doi: 10.3390/ijms22073603
Maffiuletti NA, et al