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In 2022, the global market volume of packaging-grade PET resin was estimated at 25.47 million metric tons, with projections anticipating a rise to 35.70 million metric tons by 2030, corresponding to a compound annual growth rate of 4.1% for 20232030 [3]

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Three members of the TGF family (TGF1, 2, 3) promote LOX and LOXL1-4 expression in human trabecular meshwork (sponge-like connective tissue located in the proximal side of the eye) cells via both Smad and non-Smad pathways (MAPK/JNK and AP-1) through TGFR1 and TGFR2 (Sethi et al ., 2011)

Kawaguchi Y, Kopetz S , Tran Cao HS, Panettieri E, De Bellis M, Nishioka Y, Hwang H, Wang X, Tzeng CD, Chun YS, Aloia TA, Hasegawa K, Guglielmi A, Giuliante F, Vauthey JN