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It is a fundamental concept that helps determine dosing frequency, the duration of a drug's effect, and potential accumulation in the body over time

Its activity has been associated with reduced permeability disturbances and improved resistance to mucosal injury, particularly in models involving non-steroidal anti-inflammatory drug exposure (10)

Patch-clamp electrophysiology studies

2019 Oct 1;30(4):630-655

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A leader-guided substrate tolerant RiPP brominase allows SuzukiMiyaura cross-coupling reactions for peptides and proteins