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Population-specific polymorphisms in GST genes pose significant challenges by causing variations in protein expression and function

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Darvesh AS, Aggarwal BB, Bishayee A

These events would be expected to be fatal, since G6PD is a housekeeping gene essential for basic cellular functions

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In terms of weight loss, if you have a vitamin B12 deficiency, which is likely, you will lose some of the vitamin B12 shot in the first 48 hours, but at least 50% of it will be stored in your liver