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Clinically, strategies aimed at modulating EAAC1-mediated cysteine transport and boosting endogenous GSH synthesis may hold promise for mitigating post-ischemic neurodegeneration and cognitive deficits associated with vascular dementia

Cell membranes are most vulnerable to lipid peroxidation due to their abundance of polyunsaturated fatty acids (PUFA)-containing phospholipids (PL)

In the face of hypoxic or hypercapnic challenge, maintenance of ventilatory and cardiovascular homeostasis is achieved by activation of peripheral and central chemoreceptors and subsequent modulation of this ponto-medullary respiratory control network (Marshall, 1994)

6b), suggesting that DRD2 activation drives the interaction of -arrestin2 with PKM2 to facilitate PKM2 dimerization

NAC added to risperidone has been shown to be more effective than risperidone alone in reducing irritability symptoms of ASD

Furthermore, it is worth noting that both BH4 and its oxidized form, BH2, have the capability to bind to eNOS, resulting in the production of O 2 - without the concurrent generation of NO [36]
