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Similarly, under pathogenic infection, MEKK1-MKK4-MPK3/6 is identified to function upstream of NADPH oxidase trigger H 2 O 2 production, and this, in turn, leads to the further activation of MPK3 and MPK6 [118]

2014 Nov 19;19(11):19066-77.

Patients with -thalassemia have a higher risk of stroke than the general population, which may be due to multiple factors such as iron overload, splenectomy, and hemolysis (101, 197)

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Its efficacy has also been demonstrated in patients with vascular dementia [70]
