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37 , e23175 (2023)

This index was calculated using the plasma concentrations of glutamate/(serine + glycine)

Gene expression modulation: A widely cited 2014 Organogenesis paper found that GHK-Cu could influence thousands of human genes, shifting many toward patterns associated with younger, healthier tissue behavior

Mice administered 1000 mg/kg Ltheanine showed significantly lower blood glucose levels at 15, 30, and 60 min postglucose loading compared to controls

Gene Set Enrichment Analysis (GSEA) showed enrichment of oxidative phosphorylation, glutathione metabolism, longevity regulating pathways, the NF-B signaling pathway and the TNF signaling pathway (Extended Data Fig