glutathione s-transferase mechanism action Functional and Structural Diversity of Insect S-transferases in Xenobiotic Adaptation Frontiers | Regulation of epigenetic
Description
The differential equation for cytosolic GSH is: The first term is the synthesis of GSH from glycine and glutamyl-cysteine
Biochemically, it is marked by disrupted iron metabolism, accumulation of lipid hydroperoxides (LPO), and depletion of intracellular glutathione (GSH)
10.1038/ajh.2007.12 55 OliverioM
doi:10.1002/acr.20552 116
Cohorts range from groups of 5 to 12 participants
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