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An alternative trial design would be to run two parallel trials comparing Nerinetide with placebo, one with and one without alteplase
Common Pitfall: Adjuvant vs
Cell Reports 44, 116662
Put the three together and the pitch is a loop: supply NAD+, protect NAD+, then flip on the pathways that spend it productively
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The arm or thigh injection sites are chosen for comfort and accessibility
