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Phase II conjugation reactions add large polar groups to phase I metabolites or active drug to enhance water solubility and excretion

97 The ultra-sensitive quantitative HBsAg assay has an LLOD of 0.0005 IU/mL which is 100-fold lower than those of conventional HBsAg assays

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In astrocytes, APOE4 increased de novo cholesterol synthesis despite intracellular cholesterol accumulation caused by lysosomal sequestration