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Neutralization: Glutathione catches the NAPQI and renders it harmless

Jia N, Ganesan D, Guan H et al (2025) Mitochondrial bioenergetics stimulates autophagy for pathological MAPT/Tau clearance in tauopathy neurons

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Taken together, we provide genetic evidence that glutathione plays an important role in AITC-induced growth inhibition, although further studies need to be conducted to reveal the underlying mechanisms

170 The mitophagy process involves several key steps: the reduction of m, formation of the mitophagosome, delivery of the mitophagosome to the lysosome, and finally, the degradation and recycling of mitochondrial components