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Fact: No human evidence demonstrates a dose-response relationship

The microbiota-gut-brain axis

[DOI] [PubMed] [Google Scholar] 50.Kadima W., Rabenstein D.L

doi:10.3402/jchimp.v4.25090

Verde, P., Casalino, L., Talotta, F., Yaniv, M

Intriguingly, a competitive relationship between the homologues CHAC1 and CHAC2 was observed in human embryonic stem cells (hESCs), where they play opposing roles in maintaining cellular GSH levels and regulating differentiation ( 2.4.2 CHAC1 in neuroprotection and organ injury Similar to its role in stem cell fate, CHAC1/BOTCH exhibits a dual function in regulating neuroprotection and inflammation following neuronal damage and organ injury