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Oxidative stress, therefore, drives the pathology of COPD and may increase disease progression, amplify exacerbations, and increase comorbidities through systemic oxidative stress

GHK (glycyl-L-histidyl-L-lysine) peptide has been shown to positively influence gene expression by regulating various cellular pathways associated with tissue repair, wound healing, and anti-aging mechanisms [7], and thus has potential as an anti-fibrotic agent

Industrial application of Kefiran products Kefiran is an exopolysaccharide bound to the milk kefir grains and has receiving a great interest among various industries due to its versatility and generally recognised as safe.Thoreux and Schmucker (2001) have found that kefiran could serve as a binding agent, fat replacer, emulsifier, thickening agent, stabilizer, gelling agent, and water binding in the food industry

However, pharmacokinetics alone tell an incomplete story