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But glutathione's importance extends far beyond basic antioxidant protection

Ingestion of at least 500 mg/day of EPA plus DHA is recommended by the International Society for the Study of Fatty Acids and Lipids (ISSFAL) and several other professional organizations

153 Thus, whether these observations constitute examples of bona fide on-target resistance or rather reflect the critical role of mitochondria (and in particular of the PTPC) in CDDP-elicited cell death, hence constituting examples of post-target resistance, remains an open conundrum

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