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glutathione reductase energy system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Mechanism of glutathione peroxidase (GPx)
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The pathogenesis of SCI is intricate and not yet fully understood, with current treatment options being limited
It is noteworthy that NRF2 regulates the expression of enzymes necessary to synthesize GSH, including glutamate-cysteine ligase catalytic subunit (GCLC) and its regulatory subunit (GCLM), glutathione reductase (GR), glutathione peroxidase (GPx), and several glutathione S-transferases (GST) (Suh et al
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Since estrogen action is mediated by its receptors, tissues expressing one or more ERs are considered key targets for regulation [32]
