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GP x8 binds covalently to caspase4/11 via disulfide bonding between cysteine 79 of GP x8 and cysteine 118 of caspase4 and thus restrains caspase4/11 activation, while GP x8 deficiency leads to caspase4/11induced inflammation during colitis and septic shock

The potential utility of anti-HGF/Met drugs, however, goes well beyond their use as anti-cancer agents

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Iron Overload in Patients with Chronic Liver Disease

Overdose or excess intake of vitamin B12 can cause certain side effects

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