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Cellular senescence drives age-dependent hepatic steatosis

2026 Mar 17;14(1):31

Studies suggest quercetin may help clear senescent cells (damaged cells that refuse to die and contribute to aging)

The mitochondrial matrix protein Mzm1 also contributes to zinc homeostasis by maintaining labile mitochondrial zinc pools and stabilizing the bc complex (complex III)

10.3892/or.2021.8191 [DOI] [PMC free article] [PubMed] [Google Scholar] Ward N

This local iron overload in DSCs triggers ferroptosis through reduced GSH and glutathione peroxidase four levels with the concomitant increase in lipid and cellular ROS
