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Reduction in stroke, heart attack, angina and coronary artery disease

One common strategy involves enhancing electrostatic interactions: because mucin fibres are negatively charged, mucoadhesive particles are often engineered with a positive surface charge 13

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Similar pathological changes to the liver are also observed in animal models of OXA or OXA-based chemotherapies

Although the weight loss effect of bupropion was superior in non-depressed patients compared to those suffering from depression, the fact that bupropion was well-tolerated and effective in this group of patients provides a potential valuable adjunctive therapy to elevate mood in depressed subjects in whom weight gain secondary to antidepressant therapy is an issue