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Cardiovascular and Metabolic Uncertainty Preclinical data suggest peptides may influence angiogenesis (blood vessel growth)

doi: 10.1016/j.mad.2011.02.007

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The ferroptosis activator RSL-3 and the PI3K/Akt pathway inhibitor LY294002 reversed Neuritins inhibitory effect on ferroptosis, indicating that Neuritin suppresses neuronal ferroptosis via PI3K/Akt pathway activation (Song et al., 2025)

Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: A multicentre, double-blind, randomised, controlled trial

The AS1411-triptolide conjugate shows promising potential as a targeted therapy for triple negative breast cancer, demonstrating high specificity and cytotoxicity against MDA-MB-231 cells, leading to significant tumor reduction and enhanced apoptosis in mouse models, with minimal toxicity to major organs [1012]