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Mackenzie et al., 2005

N -acetylcysteine (NAC) is a synthetic derivative of the endogenous amino acid L-cysteine (Fig

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Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB

doi: 10.1093/hmg/ddab091

Our results indicate increased DNA damage and reduced DNA repair are key targets of the dual agent treatment, and together these suggest the cancer cells are unable to repair increased DNA damage leading to higher cell death, further supporting the potential use of this dual agent as TNBC therapeutic