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Effect of dietary coenzyme Q10 plus NADH supplementation on fatigue perception and health-related quality of life in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: a prospective, randomized, double-blind, placebo-controlled trial

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Hsu et al., reported that NAC decreased p38 MAPK activity to the basal level as well as moderated LPS-induced inflammatory cytokine levels [35]

Unfortunately, we cannot make any inference as to the possible reasons for these differences in observations due to the limitations of the cross-sectional study design

Double-blind trials can come in different varieties