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Outcome of emergency ERCP for acute cholangitis in patients 90 years of age and older

E., Schelde, O., Haselmann, K

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

Additionally, CCl4 induced a decrease in anti-oxidants, including Nrf2, HO-1 and NQO-1, which were restored by treatment with SAG

The melatonin rhythm before the light exposure showed a smaller amplitude in the VB12 trial than in the placebo

BPC-157 (Body Protection Compound-157) is a laboratory-synthesized pentadecapeptide modeled on a human gastric peptide fragment