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Footnotes Conflicts of interest No potential conflict of interest relevant to this article was reported

Currently, no pharmaceuticals specifically targeting the CoQ/FSP1 pathway have reached clinical trials

Chlorogenic acid is a P450 enzyme inhibitor, which can decrease the expression of CYP2E1 and CYP1A2 (Pang et al., 2015)

Since ANGPTL3 elevates LDL levels, it may indirectly exacerbate neuroinflammation in AD

Free Radic Res 41:12011211 Ursini F, Maiorino M, Brigelius-Flohe R, Aumann KD, Roveri A, Schomburg D, Flohe L (1995) Diversity of glutathione peroxidases

"What effect does metformin have on vitamin B 12 levels?"