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HGF has two individual MET-binding interfaces, which include a high affinity NK1 (N-terminal and first kringle domain) binding site and a low affinity -chain binding site (Matsumoto et al., 2017)

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In fact, POMC and AgRP neurons modulate autonomic nerve activity in various tissues, including fat depots 34 , and these neurons can regulate fasting-induced fall in leptin levels, independently of changes in fat mass 35
Sterile water for injection, bacteriostatic water (for multi-use vials), dilute acetic acid (0.11%), or PBS at pH 7.4 are all appropriate depending on the application