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MOTS-c activates AMPK (AMP-activated protein kinase), the master metabolic switch that signals cells to burn fat when energy is low

Exosomes have been shown in early research to protect the arthritic joint by promoting cartilage repair, inhibiting inflammation of the joint lining, and helping the bone around your joints stay strong (subchondral bone remodelling)

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There are strong familial links, with most patients having first-degree relatives with the disease, and recent genome-wide association studies have identified risk loci[6]

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References 1 ReinherzELKungPCGoldsteinGLeveyRHSchlossmanSF
