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Pediatric dosing is weight-based (approximately 0.5 g of arginine per kg body weight, infused over 30 minutes), not to exceed a total of 30 g

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13 Also, recent proteomic studies have revealed that NNMT expression in the metastasis-associated stroma is critical for the differentiation of cancer-associated fibroblasts (CAF), cancer migration, and metastasis in ovarian cancer