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In both cellular compartments serine catabolism involves the conversion to glycine and then glycine oxidation to CO 2 and NH 3 , with the production of two equivalents of N 5 , N 10 -methyleneTHF

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Specific antibodies against G-CSFR (1:1000 dilution) and G-CSF (1:100 dilution), Alexa Fluor 488 goat anti-rat IgG (1:1000 dilution), Alexa Fluor 488 goat anti-mouse IgG (1:1000 dilution), U73122, and U73343 were obtained from Abcam (MA, USA)

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Thus, AR dimerization utilized tunable surfaces that are important for interdomain allostery and were found to be particularly important to bind degenerate DNA sequences, providing an explanation for how AREs that deviate considerably from the optimal textbook sequence in CaP still lead to robust transcriptional outputs

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