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Notably, microglia, as ubiquitous innate immune cells in the CNS, are pivotal contributors to neuroinflammation, participating in both anti-inflammatory and pro-inflammatory responses (44)

In addition, H 2 O 2 can also react with Met, favoring methionine sulfoxide (MetO) formation, which is also reversed by the enzyme methionine sulfoxide reductase (MSR), being also considered as a redox signaling modification (Martnez-Klimova et al