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Hohnloser SH, Hijazi Z, Thomas L, Alexander JH, Amerena J, Hanna M, et al

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doi: 10.1016/j.psj.2019.11.069 33 Al-BatshanHAAl-MufarrejSIHomaidanAAQureshiMA

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So, it is now established that tolerance to respiratory depression is lower than the tolerance to analgesia (Mohammed et al., 2013) and might explain fatal overdoses (White and Irvine, 1999)

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Dihexa-treated rats quickly regained motor performance equivalent to sham-operated controls, and significantly surpassed those receiving a placebo

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