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Research-grade refers to compounds intended for controlled laboratory research environments and not for clinical or personal use.

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PEA is thought to work by supporting the inflammatory response through the PPAR-a receptor, COX-2 and through effects on NF-kappaB signaling while also by restoring balance in the endocannabinoid system

This concern is particularly relevant for individuals with pre-existing insulin resistance or those using the peptide long-term without breaks

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